Brisbane business raided over missing man

Mr Griffiths' family and police are concerned as he hasn't contacted anyone for more than three weeks.

Detectives investigating his disappearance raided a business at Coopers Plains in Brisbane's south on Thursday morning.

A mobile police unit remains at the scene with detectives set to make a public appeal for information later in the day.

"Anyone with knowledge of his whereabouts or information about the missing person is urged to contact police," a police statement said.

Mr Griffiths is Caucasian with sandy hair and hazel eyes and has tattoos on his neck.